Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644901 | 0.86 | MAPK1 (0.56) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL8419387 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL8421130 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL607963 | 0.85 | MAPK1 (0.54) | ALDH1A1HPGDMAPK1TSHRSLC16A3 | |
| SCHEMBL28513100 | 0.83 | MAPK1 (0.49) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL5101721 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL1644885 | 0.82 | MAPK1 (0.59) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL7473218 | 0.82 | SLC16A3 (0.49) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL7055476 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPK1TSHRHTT | |
| SCHEMBL9429255 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPK1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |