Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868551 | 0.92 | P4HTM (0.47) | P4HTMEGFRALDH1A1CYP2C19CA12 | |
| SCHEMBL8868506 | 0.91 | P4HTM (0.51) | P4HTMEGFRATMALDH1A1HTT | |
| SCHEMBL8868894 | 0.89 | P4HTM (0.51) | P4HTMEGFRALDH1A1HTTCA12 | |
| SCHEMBL8869114 | 0.89 | PTPN1 (0.51) | P4HTMALDH1A1CA12CA1CA2 | |
| SCHEMBL9140990 | 0.87 | P4HTM (0.66) | P4HTMEGFRATM | |
| SCHEMBL8868396 | 0.86 | HDAC3 (0.54) | P4HTMEGFRALDH1A1CA12CA1 | |
| SCHEMBL7874562 | 0.85 | EGFR (0.43) | P4HTMEGFRATMALDH1A1HTT | |
| SCHEMBL9137568 | 0.85 | P4HTM (0.55) | P4HTMEGFRATMALDH1A1HTT | |
| SCHEMBL8869078 | 0.85 | P4HTM (0.53) | P4HTMEGFRCA12CA1CA2 | |
| SCHEMBL8869119 | 0.84 | L3MBTL1 (0.56) | P4HTMALDH1A1GAAPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |