Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869400 | 0.93 | CA12 (0.42) | EGFRP4HTMALDH1A1CYP2C19CA12 | |
| SCHEMBL7869445 | 0.92 | PKM (0.43) | EGFRATMP4HTMALDH1A1CYP1A2 | |
| SCHEMBL7874570 | 0.90 | EGFR (0.44) | EGFRP4HTMALDH1A1HTTCA12 | |
| SCHEMBL7862667 | 0.90 | PTPN1 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL7870480 | 0.87 | SCN3A (0.46) | P4HTMCA12CA1CA2CA9 | |
| SCHEMBL7869457 | 0.87 | P4HTM (0.47) | P4HTMMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL7867803 | 0.87 | L3MBTL1 (0.52) | P4HTMALDH1A1MEN1KMT2ACXCR1 | |
| SCHEMBL7871607 | 0.87 | ALDH1A1 (0.52) | P4HTMALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7871681 | 0.86 | EGFR (0.46) | EGFRP4HTMCA12CA1CA2 | |
| SCHEMBL8868261 | 0.85 | P4HTM (0.49) | EGFRATMP4HTMALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |