Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867655 | 0.87 | PTPN1 (0.65) | MITFPTPN1RAB9ANPC1MEN1 | |
| SCHEMBL12310177 | 0.86 | RAB9A (0.73) | MITFPTPN1RAB9ANPC1MEN1 | |
| SCHEMBL4740034 | 0.86 | PTPN1 (0.63) | MITFPTPN1RAB9ANPC1MEN1 | |
| SCHEMBL8868950 | 0.85 | CNR1 (0.59) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL10684470 | 0.84 | PTPN1 (0.88) | MITFPTPN1RAB9ANPC1MEN1 | |
| SCHEMBL8867874 | 0.84 | KMT2A (0.58) | PTPN1RAB9ANPC1MEN1KMT2A | |
| SCHEMBL8868321 | 0.84 | CACNA1B (0.63) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL8867048 | 0.84 | POLB (0.71) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL8867477 | 0.84 | NPC1 (0.71) | RAB9ANPC1MEN1KMT2ALMNA | |
| SCHEMBL8867694 | 0.83 | PTPN1 (0.62) | PTPN1RAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |