Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.73 |
| ▸ | RAB9A | P51151 | 10/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868420 | 0.88 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL29684837 | 0.84 | RAB9A (0.71) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL308069 | 0.83 | NPC1 (0.75) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL8771200 | 0.80 | NPC1 (0.89) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL19392293 | 0.80 | NPC1 (0.89) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL2063276 | 0.79 | NPC1 (0.86) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL9037744 | 0.79 | ALDH1A1 (0.60) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL1929165 | 0.79 | NPC1 (0.85) | NPC1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL12136717 | 0.78 | KMT2A (1.00) | NPC1RAB9AMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL6967966 | 0.78 | ALDH1A1 (0.59) | NPC1RAB9AMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152443-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHI MEI CORPORATION (TW) | 2017-06-01 | — | — | US | disclosed |
| US-20170152443-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT | CHI MEI CORPORATION (TW) | 2017-06-01 | — | — | US | disclosed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |