Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868432 | 0.93 | NLRP3 (0.49) | ALDH1A1LMNAMAPTP4HTMKMT2A | |
| SCHEMBL8868784 | 0.93 | P4HTM (0.51) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL9140771 | 0.92 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8869220 | 0.90 | P4HTM (0.54) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8868823 | 0.90 | SMN1; SMN2 (0.50) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8868488 | 0.90 | LMNA (0.51) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8868729 | 0.89 | P4HTM (0.52) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8868489 | 0.89 | P4HTM (0.47) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8869766 | 0.89 | P4HTM (0.53) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM | |
| SCHEMBL8867833 | 0.88 | P4HTM (0.49) | ALDH1A1LMNASMN1; SMN2MAPTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |