Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867596 | 0.89 | MAPT (0.51) | KMT2ALMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL8868523 | 0.88 | KMT2A (0.55) | KMT2ALMNAMAPTGAAALOX12 | |
| SCHEMBL8868516 | 0.88 | KMT2A (0.55) | KMT2ALMNAMAPTGAAALOX12 | |
| SCHEMBL8868116 | 0.84 | MAPT (0.60) | KMT2AMAPTMEN1HTTALDH1A1 | |
| SCHEMBL8867437 | 0.83 | ALDH1A1 (0.50) | KMT2ALMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL8867071 | 0.82 | KMT2A (0.53) | KMT2ALMNAMAPTGAAKDM4E | |
| SCHEMBL8868163 | 0.82 | MAPT (0.61) | KMT2ALMNAMAPTGAACYP1A2 | |
| SCHEMBL8868030 | 0.80 | KDM4E (0.43) | KMT2ALMNAMAPTGAAALOX12 | |
| SCHEMBL8867582 | 0.77 | MAPT (0.53) | KMT2ALMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL8867588 | 0.77 | MAPT (0.53) | KMT2ALMNAMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |