Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868021 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HTTALOX12HPGD | |
| SCHEMBL8868024 | 0.88 | ALDH1A1 (0.44) | KDM4EALDH1A1HTTALOX12HPGD | |
| SCHEMBL8867437 | 0.85 | ALDH1A1 (0.50) | KDM4ERHOAALDH1A1GAAMAPT | |
| SCHEMBL8868715 | 0.84 | CA12 (0.51) | RHOAMAPK1MAPTMEN1KMT2A | |
| SCHEMBL8867071 | 0.83 | KMT2A (0.53) | KDM4ERHOAALDH1A1GAAMAPT | |
| SCHEMBL8867596 | 0.82 | MAPT (0.51) | KDM4ERHOAALDH1A1HTTHPGD | |
| SCHEMBL8868531 | 0.80 | KMT2A (0.56) | KDM4ERHOAALDH1A1HTTALOX12 | |
| SCHEMBL8868163 | 0.77 | MAPT (0.61) | KDM4ERHOAALDH1A1HTTGAA | |
| SCHEMBL8867685 | 0.73 | MAOB (0.46) | RHOAMAPTPKMMEN1KMT2A | |
| SCHEMBL13754517 | 0.73 | ALOX12 (0.62) | KDM4EALDH1A1HTTALOX12HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |