Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RHOA | P61586 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867056 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL8867437 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1CYP3A4MEN1KDM4E | |
| SCHEMBL8867062 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL8867294 | 0.85 | MAOB (0.53) | KMT2AHSD17B10MEN1RHOAMAPT | |
| SCHEMBL8868163 | 0.85 | MAPT (0.61) | KMT2AALDH1A1CYP3A4MEN1KDM4E | |
| SCHEMBL8867596 | 0.84 | MAPT (0.51) | KMT2AALDH1A1KDM4ERHOAMAPT | |
| SCHEMBL8868030 | 0.83 | KDM4E (0.43) | KMT2AALDH1A1MEN1KDM4ERHOA | |
| SCHEMBL8868531 | 0.82 | KMT2A (0.56) | KMT2AALDH1A1MEN1KDM4ERHOA | |
| SCHEMBL8867766 | 0.75 | NPC1 (0.57) | KMT2AALDH1A1MEN1RHOAMAPT | |
| SCHEMBL8867859 | 0.75 | CA1 (0.51) | KMT2AALDH1A1MEN1RHOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |