SCHEMBL886935

SCHEMBL886935

CCN[C](NCC)NCC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 1/20 0.50
KDM4A O75164 1/20 0.42
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
KMT2A Q03164 1/20 0.36
TP53 P04637 1/20 0.36
MCL1 Q07820 1/20 0.35
GAA P10253 1/20 0.33
FAAH O00519 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17120970 0.70 MMP1 (0.43) ALDH1A1CYP3A4KDM4AMMP1MMP2
SCHEMBL11403382 0.70
SCHEMBL363515 0.70
SCHEMBL1272671 0.67
SCHEMBL80644 0.67
SCHEMBL3060269 0.67 MMP1 (0.48) ALDH1A1CYP3A4KDM4AMMP1MMP2
SCHEMBL17985472 0.67
SCHEMBL1743801 0.67
SCHEMBL3062029 0.67 ALDH1A1 (0.62) ALDH1A1CYP3A4KDM4AMMP1MMP2
SCHEMBL1278188 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938501-B1 PROCESS FOR THE PURIFICATION OF HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST FROM RECOMBINANT E. COLI AVENTIS BULK S P A (IT) 2004-07-28 EP claimed
EP-0820468-B1 PROCESS FOR THE PURIFICATION OF GLYCOPROTEINS LIKE ERYTHROPOIETIN LEPETIT SPA (IT) 2000-06-28 EP claimed
EP-3445721-B1 WATER TREATMENT APPARATUS PALL CORP (US) 2021-03-17 EP disclosed
EP-1888213-B1 FLUIDICS DEVICE BIO RAD LABORATORIES INC (US) 2017-10-18 EP disclosed
US-8491791-B2 Fluidics device BIO-RAD LABORATORIES, INC. (US) 2013-07-23 US disclosed
US-20120309644-A1 FLUIDICS DEVICE BIO-RAD LABORATORIES, INC. (US) 2012-12-06 US disclosed
US-8246832-B2 Fluidics device BIO-RAD LABORATORIES, INC. (US) 2012-08-21 US disclosed
EP-1907089-B1 SEPARATION OF PROTEINS BASED ON ISOELECTRIC POINT USING SOLID-PHASE BUFFERS BIO RAD LABORATORIES (US) 2011-11-23 EP disclosed
US-20090179146-A1 FLUIDICS DEVICE BIO-RAD LABORATORIES, INC. 2009-07-16 US disclosed
US-20070039891-A1 Separation of proteins based on isoelectric point using solid-phase buffers CIPHERGEN BIOSYSTEMS, INC. 2007-02-22 US disclosed
US-20060116509-A1 Manufacture of limonoid compounds THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2006-06-01 US disclosed
WO-2006058299-A2 MANUFACTURE OF LIMONOID COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2006-06-01 WO disclosed