SCHEMBL886955

SCHEMBL886955

[SiH3]OCCCCC=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.44
SIGMAR1 Q99720 2/20 0.41
PAM P19021 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TBXAS1 P24557 1/20 0.39
PPARA Q07869 1/20 0.38
HTR2A P28223 3/20 0.38
LTB4R Q15722 1/20 0.37
LTB4R2 Q9NPC1 1/20 0.37
MAOB P27338 1/20 0.37
CHRNA7 P36544 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL886961 0.94 IDO1 (0.46) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL1470885 0.86 IDO1 (0.48) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL12802434 0.84 HRH3 (0.41) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL3795388 0.82 SIGMAR1 (0.50) IDO1SIGMAR1PAMTBXAS1HTR2A
SCHEMBL3240089 0.80 IDO1 (0.52) IDO1SIGMAR1PAMTBXAS1HTR2A
SCHEMBL7110889 0.79 IDO1 (0.48) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL10889742 0.79 IDO1 (0.48) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL14142737 0.77 IDO1 (0.41) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL5535947 0.77 IDO1 (0.41) IDO1SIGMAR1PAMMEN1KMT2A
SCHEMBL5535943 0.77 IDO1 (0.41) IDO1SIGMAR1PAMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833905-B1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER MICHELIN & CIE (FR) 2013-08-07 EP claimed
US-8461269-B2 Elastomeric composition reinforced with a funtionalized non-aromatic vinyl polymer filler Micheln Recherche et Technique S.A. (CH) 2013-06-11 US claimed
US-20110021702-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2011-01-27 US claimed
US-7820771-B2 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S. A. (CH) 2010-10-26 US claimed
EP-1838765-B1 FUNCTIOANALISED POLYVINYLAROMATIC NANOPARTICLES MICHELIN RECH TECH (CH) 2010-08-04 EP claimed
US-20100022714-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2010-01-28 US claimed
US-20090270558-A1 Functionalized Polyvinylaromatic Nanoparticles MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-10-29 US claimed
EP-2044148-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER Societe de Technologie Michelin (FR) 2009-04-08 EP claimed
EP-2041207-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES Societe de Technologie Michelin STM (FR) 2009-04-01 EP claimed
US-20080132644-A1 copolymer of styrene, ethylvinylbenzene, divinylbenzene and trimethoxysilylpropyl(meth)acrylate, being in the form of nanobeads as reinforcing filler; tires or rubber semi-finished products intended for these tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-06-05 US claimed
WO-2008003435-A1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
WO-2008003434-A1 FUNCTIONALIZED VINYL POLYMER NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2008-01-10 WO claimed
EP-1838765-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES Michelin Recherche et Technique S.A. (CH) 2007-10-03 EP claimed
EP-1833905-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER Societe de Technologie Michelin (FR) 2007-09-19 EP claimed
WO-2006069793-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO claimed
WO-2006069792-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO claimed
EP-2044148-B1 ELASTOMERIC COMPOSITION REINFORCED WITH A FUNCTIONALIZED NON-AROMATIC VINYL POLYMER FILLER MICHELIN & CIE (FR) 2017-04-05 EP disclosed
US-8883929-B2 Functionalized vinyl polymer nanoparticles COMPAGNIE GENERALE DES ETABLISSEMENTS (FR) 2014-11-11 US disclosed
WO-2006069793-A1 ELASTOMER COMPOSITION WHICH IS REINFORCED WITH A FUNCTIONALISED POLYVINYLAROMATIC FILLER SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO disclosed
WO-2006069792-A1 FUNCTIANALISED POLYVINYLAROMATIC NANOPARTICLES SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2006-07-06 WO disclosed