Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868373 | 0.94 | P4HTM (0.45) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868202 | 0.94 | ALDH1A1 (0.45) | P4HTMSMN1; SMN2MAPTNFKB1ALDH1A1 | |
| SCHEMBL8868835 | 0.92 | NPC1 (0.52) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868748 | 0.91 | NPC1 (0.49) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868297 | 0.91 | P4HTM (0.47) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868359 | 0.91 | P4HTM (0.48) | P4HTMRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8869536 | 0.91 | POLB (0.48) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868801 | 0.91 | CA2 (0.46) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9143419 | 0.90 | P4HTM (0.48) | P4HTMRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL8868336 | 0.88 | P4HTM (0.44) | P4HTMRAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |