Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871464 | 0.92 | RORC (0.51) | POLBRORCNR1H4PRMT3 | |
| SCHEMBL8871473 | 0.92 | RORC (0.51) | POLBRORCNR1H4PRMT3 | |
| SCHEMBL8870087 | 0.91 | MME (0.47) | MMEACENR1H4PRMT3HIF1A | |
| SCHEMBL8870354 | 0.85 | HPSE (0.47) | MMEACENR1H4PRMT3 | |
| SCHEMBL8870350 | 0.85 | HPSE (0.47) | MMEACENR1H4PRMT3 | |
| SCHEMBL8871638 | 0.81 | ALDH1A1 (0.46) | PRMT3 | |
| SCHEMBL8871632 | 0.81 | ALDH1A1 (0.46) | PRMT3 | |
| SCHEMBL7568821 | 0.80 | SELP (0.41) | MMEACEPRMT3 | |
| SCHEMBL8870888 | 0.77 | ITGB1 (0.42) | MMEACEITGB1ITGA4 | |
| SCHEMBL8870999 | 0.77 | ITGB1 (0.43) | MMEACEITGB1ITGA4PRMT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |