Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871632 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1MAPTPRMT3 | |
| SCHEMBL8871464 | 0.86 | RORC (0.51) | PRMT3PPID | |
| SCHEMBL8871473 | 0.86 | RORC (0.51) | PRMT3PPID | |
| SCHEMBL8869745 | 0.81 | MME (0.50) | PRMT3 | |
| SCHEMBL8870371 | 0.80 | ALDH1A1 (0.60) | ALDH1A1MAPK1L3MBTL1MAPTENPP2 | |
| SCHEMBL8870545 | 0.80 | CCKBR (0.44) | PRMT3 | |
| SCHEMBL8870550 | 0.80 | CCKBR (0.44) | PRMT3 | |
| SCHEMBL8870350 | 0.77 | HPSE (0.47) | PRMT3 | |
| SCHEMBL8870354 | 0.77 | HPSE (0.47) | PRMT3 | |
| SCHEMBL8870936 | 0.75 | PKM (0.48) | ALDH1A1MAPTPRMT3PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |