Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA4 | P22748 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564926 | 0.79 | CRBN (0.52) | CRBNDDB1CA1CA2CA4 | |
| SCHEMBL27278428 | 0.71 | CRBN (0.39) | CRBNDDB1CA1CA2CA4 | |
| SCHEMBL7021931 | 0.71 | CA1 (0.57) | CRBNCA1CA2ALDH1A1PKM | |
| SCHEMBL8377720 | 0.69 | — | — | |
| SCHEMBL24755086 | 0.65 | CRBN (0.50) | CRBNDDB1ALDH1A1LMNAPKM | |
| SCHEMBL27581645 | 0.65 | CRBN (0.50) | CRBNDDB1ALDH1A1LMNAPKM | |
| SCHEMBL13736277 | 0.64 | CA1 (0.44) | CA1CA2ALDH1A1LMNA | |
| SCHEMBL5963506 | 0.64 | — | — | |
| SCHEMBL710129 | 0.64 | — | — | |
| SCHEMBL35355 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12467098-B2 | Methylated markers for colorectal cancer | QUEST DIAGNOSTICS INVESTMENTS LLC (US) | 2025-11-11 | — | — | US | claimed |
| US-20250179583-A1 | METHYLATED DNA MARKERS AND ASSAYS THEREOF FOR USE IN DETECTING COLORECTAL CANCER | CEDARS-SINAI MEDICAL CENTER (US) | 2025-06-05 | — | — | US | claimed |
| EP-4486917-A2 | METHYLATED DNA MARKERS AND ASSAYS THEREOF FOR USE IN DETECTING COLORECTAL CANCER | Cedars-Sinai Medical Center (US) | 2025-01-08 | — | — | EP | claimed |
| CN-118755827-A | Auxiliary detection method and kit for high-risk group of gastric cancer | 青岛万物新生生物医疗科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-118703628-A | DNA methylation marker auxiliary detection kit and detection method | 青岛万物新生生物医疗科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118531122-A | Intestinal cell DNA methylation marker detection kit and detection method | 青岛万物新生生物医疗科技有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-113668068-B | Genome methylation library and preparation method and application thereof | 广州滴纳生物科技有限公司 | 2024-07-19 | — | — | CN | claimed |
| WO-2023168345-A2 | METHYLATED DNA MARKERS AND ASSAYS THEREOF FOR USE IN DETECTING COLORECTAL CANCER | CEDARS-SINAI MEDICAL CENTER (US) | 2023-09-07 | — | — | WO | claimed |
| US-20230212685-A1 | METHYLATED MARKERS FOR COLORECTAL CANCER | QUEST DIAGNOSTICS INVESTMENTS LLC (US) | 2023-07-06 | — | — | US | claimed |
| US-11486007-B2 | Methylated markers for colorectal cancer | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2022-11-01 | — | — | US | claimed |
| EP-3101141-A2 | METHOD FOR METHYLATION ANALYSIS | Epigenomics AG (DE) | 2016-12-07 | — | — | EP | claimed |
| EP-2479289-B1 | Method for methylation analysis | EPIGENOMICS AG (DE) | 2016-04-06 | — | — | EP | claimed |
| WO-2015187823-A2 | METHYLATED MARKERS FOR COLORECTAL CANCER | QUEST DIAGNOSTICS INVESTMENTS INCORPORATED (US) | 2015-12-10 | — | — | WO | claimed |
| US-8623599-B2 | Method for methylation analysis | EPIGENOMICS AG (DE) | 2014-01-07 | — | — | US | claimed |
| EP-2479289-A2 | Method for methylation analysis | Epigenomics AG (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20110009277-A1 | METHOD FOR METHYLATION ANALYSIS | NEW DAY DIAGNOSTICS LLC | 2011-01-13 | — | — | US | claimed |
| EP-2152902-A2 | METHOD FOR METHYLATION ANALYSIS | Epigenomics AG (DE) | 2010-02-17 | — | — | EP | claimed |
| US-20100021902-A1 | Method for methylation-selective amplification | EPIGENOMICS AG (DE) | 2010-01-28 | — | — | US | claimed |
| EP-2143807-A1 | Method for methylation-selective amplification | Epigenomics AG (DE) | 2010-01-13 | — | — | EP | claimed |
| WO-2008149237-A2 | METHOD FOR METHYLATION ANALYSIS | EPIGENOMICS AG (DE) | 2008-12-11 | — | — | WO | claimed |