Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL886979 | 0.79 | CRBN (0.47) | CRBNDDB1PKMCA1CA2 | |
| SCHEMBL7021931 | 0.74 | CA1 (0.57) | CRBNPKMCA1CA2 | |
| SCHEMBL11733020 | 0.70 | HTR6 (0.31) | HTR6 | |
| SCHEMBL35355 | 0.69 | — | — | |
| SCHEMBL28426470 | 0.67 | CRBN (0.58) | CRBNDDB1PKMDUT | |
| SCHEMBL11815477 | 0.64 | POLB (0.51) | CA1CA2CA9 | |
| SCHEMBL8560725 | 0.64 | CA1 (0.59) | CA1CA2 | |
| SCHEMBL5963506 | 0.64 | — | — | |
| SCHEMBL710129 | 0.64 | — | — | |
| SCHEMBL3762 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | claimed |
| EP-0877022-A1 | Synthesis of the sulfonylpyrimidine derivatives with anticancer activity | Herbos d.d. (HR) | 1998-11-11 | — | — | EP | disclosed |