Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.33 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200235 | 0.86 | GAA (0.39) | CA2CA1CA9CA12CA4 | |
| SCHEMBL9057128 | 0.86 | CA1 (0.32) | CA2CA1CA9CA12CA4 | |
| SCHEMBL5655444 | 0.77 | CA2 (0.42) | CA2CA1CA9CA12CA7 | |
| SCHEMBL10464956 | 0.76 | CA2 (0.31) | CA2CA1CA4 | |
| SCHEMBL4358027 | 0.76 | CA2 (0.41) | CA2CA1CA9CA12CA4 | |
| SCHEMBL9020904 | 0.74 | CA2 (0.33) | CA2 | |
| SCHEMBL9020911 | 0.74 | CA2 (0.33) | CA2 | |
| SCHEMBL27961605 | 0.74 | PTGES2 (0.43) | CA2CA1CA9CA12CA4 | |
| SCHEMBL5652598 | 0.73 | CA2 (0.44) | CA2CA1CA9CA12CA7 | |
| SCHEMBL8563204 | 0.72 | ALDH1A1 (0.32) | NPC1ALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679670-A | CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1997-10-21 | — | — | US | disclosed |
| US-5378703-A | FOR CONTROLLING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1995-01-03 | — | — | US | disclosed |