Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870042 | 1.00 | SIGMAR1 (0.57) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8870619 | 0.99 | SIGMAR1 (0.56) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8869966 | 0.92 | HTR1A (0.53) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8870746 | 0.92 | HTR1A (0.53) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8870600 | 0.91 | HTR1A (0.54) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL7756745 | 0.83 | HTR1A (0.63) | HTR1AHTR2C | |
| SCHEMBL7756727 | 0.82 | HTR1A (0.64) | HTR1AHTR2C | |
| SCHEMBL8116414 | 0.80 | SIGMAR1 (0.60) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8870613 | 0.80 | SIGMAR1 (0.60) | SIGMAR1TP53CYP1A2CYP2D6TSHR | |
| SCHEMBL8116630 | 0.78 | SIGMAR1 (0.58) | SIGMAR1TP53CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |