Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.63 |
| ▸ | HTR2C | P28335 | 7/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756727 | 0.99 | HTR1A (0.64) | HTR1AHTR2CDRD2HTR2ATMEM97 | |
| SCHEMBL7763020 | 0.88 | HTR1A (0.62) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL467277 | 0.87 | HTR1A (0.61) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL8870746 | 0.85 | HTR1A (0.53) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL8869966 | 0.85 | HTR1A (0.53) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL8870600 | 0.84 | HTR1A (0.54) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL8948040 | 0.84 | HTR1A (0.61) | HTR1AHTR2CDRD2HTR2A | |
| SCHEMBL8870102 | 0.83 | SIGMAR1 (0.57) | HTR1AHTR2C | |
| SCHEMBL8870042 | 0.83 | SIGMAR1 (0.57) | HTR1AHTR2C | |
| SCHEMBL8948002 | 0.83 | HTR1A (0.87) | HTR1AHTR2CDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |