Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871080 | 0.80 | LMNA (0.39) | PKMRAB9AMAPTLMNANPC1 | |
| SCHEMBL8871087 | 0.80 | LMNA (0.39) | PKMRAB9AMAPTLMNANPC1 | |
| SCHEMBL5284350 | 0.76 | GAA (0.63) | GAAPKMCA12CA1CA9 | |
| SCHEMBL25840841 | 0.76 | NPC1 (0.55) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL7867128 | 0.75 | FFAR1 (0.55) | RAB9AMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL3901459 | 0.74 | NPC1 (0.42) | GAACA1CA2RAB9AMAPT | |
| SCHEMBL4597724 | 0.73 | ALDH1A1 (0.44) | GAACA2MAPTALDH1A1USP2 | |
| SCHEMBL19386035 | 0.73 | NPC1 (0.47) | GAARAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL13855069 | 0.73 | HDAC1 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7046413 | 0.73 | FFAR1 (0.44) | RAB9AMAPTLMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |