Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871080 | 1.00 | LMNA (0.39) | LMNACCKBRALDH1A1PRMT3RAB9A | |
| SCHEMBL8870937 | 0.86 | PKM (0.48) | LMNAALDH1A1PRMT3RAB9AMAPT | |
| SCHEMBL8870936 | 0.86 | PKM (0.48) | LMNAALDH1A1PRMT3RAB9AMAPT | |
| SCHEMBL8870526 | 0.80 | GAA (0.48) | LMNAALDH1A1RAB9AMAPTTSHR | |
| SCHEMBL7577218 | 0.78 | CCKAR (0.42) | CCKBRPRMT3 | |
| SCHEMBL8870127 | 0.76 | SIGMAR1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL8870137 | 0.76 | SIGMAR1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL8871464 | 0.75 | RORC (0.51) | PRMT3RAB9APPID | |
| SCHEMBL8871473 | 0.75 | RORC (0.51) | PRMT3RAB9APPID | |
| SCHEMBL8871632 | 0.73 | ALDH1A1 (0.46) | ALDH1A1PRMT3MAPTPPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |