Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 2/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870784 | 1.00 | IDO1 (0.34) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| SCHEMBL8870811 | 1.00 | IDO1 (0.34) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| Aseripide SCHEMBL4096803 | 0.93 | PTGS2 (0.36) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| Aseripide SCHEMBL4096800 | 0.93 | PTGS2 (0.36) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| Aseripide SCHEMBL29387471 | 0.93 | PTGS2 (0.36) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| Aseripide SCHEMBL5274420 | 0.93 | PTGS2 (0.36) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| SCHEMBL8870841 | 0.88 | CASR (0.36) | CCKBRCYP1A2CYP2C19PRMT5WDR77 | |
| SCHEMBL8870833 | 0.88 | CASR (0.36) | CCKBRCYP1A2CYP2C19PRMT5WDR77 | |
| SCHEMBL8870912 | 0.88 | PTGS2 (0.36) | IDO1CCKBRCYP1A2CYP2C19RORC | |
| SCHEMBL8870373 | 0.87 | BACE1 (0.34) | RORCUSP30NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |