Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 10/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870842 | 1.00 | ACE (0.39) | ACELMNAFFAR2HTTCTSS | |
| SCHEMBL8871032 | 0.82 | ACE (0.46) | ACELMNAFFAR2HTT | |
| SCHEMBL8860593 | 0.81 | POLB (0.40) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL8870726 | 0.80 | ACE (0.46) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL8870261 | 0.80 | ACE (0.46) | ACELMNAFFAR2HTTALDH1A1 | |
| SCHEMBL7660623 | 0.78 | HSD17B10 (0.44) | FFAR2ALDH1A1POLB | |
| SCHEMBL8870412 | 0.76 | USP30 (0.36) | — | |
| SCHEMBL8870606 | 0.76 | USP30 (0.36) | — | |
| SCHEMBL8860462 | 0.74 | SIGMAR1 (0.39) | ACECTSSCTSKALDH1A1POLB | |
| SCHEMBL8860452 | 0.74 | SIGMAR1 (0.39) | ACECTSSCTSKALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |