Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1241980 | 0.80 | IDH1 (0.43) | IDH1KMT2ANPC1RAB9ATAS1R3 | |
| SCHEMBL1241626 | 0.72 | EPHX2 (0.49) | IDH1NPC1RAB9AALDH1A1TAS1R3 | |
| SCHEMBL31092447 | 0.71 | SMN1; SMN2 (0.55) | KMT2AL3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL6938812 | 0.71 | KDM4E (0.50) | KMT2ARAB9AMEN1ALDH1A1TAS1R3 | |
| SCHEMBL6938817 | 0.71 | KDM4E (0.50) | KMT2ARAB9AMEN1ALDH1A1TAS1R3 | |
| SCHEMBL11151926 | 0.70 | ABCC1 (0.50) | MAPK8KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL29793294 | 0.70 | CXCL8 (0.55) | MAPK10KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL396120 | 0.70 | CXCL8 (0.55) | MAPK10KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL632301 | 0.68 | L3MBTL1 (0.49) | KMT2ANPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL14928325 | 0.67 | ACHE (0.54) | MAPK10KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641775-A | 3-phenylureido-1,5-benzodiazepine-diones useful as gastrin or antagonists | GLAXO SPA (IT) | 1997-06-24 | — | — | US | disclosed |