Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.68 |
| ▸ | MPO | P05164 | 5/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871701 | 0.97 | HTR1A (0.64) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8871437 | 0.94 | MPO (0.64) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8871262 | 0.93 | HTR1A (0.67) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8871148 | 0.87 | HTR7 (0.56) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8871338 | 0.87 | HTR1A (0.58) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8870468 | 0.86 | HTR1A (0.64) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8872120 | 0.85 | HTR7 (0.52) | HTR1AMPOSLC6A4HTR7 | |
| SCHEMBL8557344 | 0.84 | HTR1A (0.76) | HTR1AMPOSLC6A4HTR7KCNH2 | |
| SCHEMBL8870689 | 0.83 | HTR1A (0.58) | HTR1AKCNH2HTR6 | |
| SCHEMBL8870688 | 0.83 | HTR1A (0.70) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693655-A | 3-indolylpiperidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-02 | — | — | US | disclosed |