Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044317 | 0.85 | ALDH1A1 (0.42) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL27785479 | 0.81 | ALDH1A1 (0.36) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL1565803 | 0.79 | HSD17B10 (0.46) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1758691 | 0.77 | HSD17B10 (0.44) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL10506090 | 0.77 | HSD17B10 (0.47) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL10753156 | 0.76 | BACE1 (0.41) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL9355248 | 0.76 | BACE1 (0.41) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL14003554 | 0.75 | GABRA5 (0.46) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL7192491 | 0.75 | HSD17B10 (0.46) | HSD17B10GABRA5GABRB2BACE1ALDH1A1 | |
| SCHEMBL22869105 | 0.74 | CTPS1 (0.41) | HSD17B10ALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665717-A | Carbacephalosporin compound, their preparation and use | PFIZER INC. (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0689540-A1 | CARBACEPHALOSPORIN COMPOUND, THEIR PREPARATION AND USE | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021633-A1 | CARBACEPHALOSPORIN COMPOUND, THEIR PREPARATION AND USE | SMITHKLINE BEECHAM PLC (GB) | 1994-09-29 | — | — | WO | disclosed |
| US-4534896-A | 3-Acylamino-2-oxoazetidine-1-(β-oxopropionic acid) | E. R. SQUIBB & SONS, INC. (US) | 1985-08-13 | — | — | US | disclosed |