SCHEMBL887121

SCHEMBL887121

NC1=NC(=S)N=C2N=CN=C12

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MPO P05164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134491 0.78 MPO (0.31) MPO
SCHEMBL545834 0.75 MPO (0.33) MPO
SCHEMBL183647 0.71 MPO (0.36) MPO
SCHEMBL11805243 0.66 MPO (0.33) MPO
SCHEMBL3801963 0.62 MPO (0.36) MPO
SCHEMBL7452613 0.62
SCHEMBL7456782 0.62
SCHEMBL4146881 0.61
SCHEMBL157261 0.61 MPO (0.33) MPO
SCHEMBL7617970 0.60 MPO (0.41) MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002509155-A 2002-03-26 JP claimed
EP-1047705-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 2000-11-02 EP claimed
US-6054568-A Nucleobase oligomers THE PERKIN-ELMER CORPORATION (US) 2000-04-25 US claimed
WO-1999036429-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 1999-07-22 WO claimed
US-20250313838-A1 NUCLEIC ACID FOR TRANSFECTION AGC Inc. (JP) 2025-10-09 US disclosed
EP-4585684-A1 NUCLEIC ACID FOR TRANSFECTION AGC INC. (JP) 2025-07-16 EP disclosed
CN-119731318-A Nucleic acid for transfection AGC株式会社 2025-03-28 CN disclosed
WO-2024141901-A1 HEAT-BASED TRANSFER OF REACTION PRODUCTS MADE IN SITU TO A PLANAR SUPPORT MOLECULENT AB (SE) 2024-07-04 WO disclosed
EP-4320263-B1 DETECTION OF PROXIMITY ASSAY PRODUCTS IN SITU MOLECULENT AB (SE) 2024-06-19 EP disclosed
US-20240190957-A1 HIGH-THROUGHPUT METHODS FOR ANALYZING AND AFFINITY-MATURING AN ANTIGEN-BINDING MOLECULE 10X GENOMICS, INC. 2024-06-13 US disclosed
US-20240192225-A1 METHOD FOR EPITOPE BINNING OF NOVEL MONOCLONAL ANTIBODIES 10X GENOMICS, INC. 2024-06-13 US disclosed
US-20240140977-A1 REVERSIBLE TERMINATORS ANSA BIOTECHNOLOGIES, INC. 2024-05-02 US disclosed
WO-1997001646-A2 ELECTROCHEMICAL DETECTION OF NUCLEIC ACID HYBRIDIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-01-16 WO disclosed
EP-0411158-B1 Process for producing nucleosides by using phosphorylases obtainable from Bacillus stearothermophilus YAMASA SHOYU KK (JP) 1996-05-29 EP disclosed
US-5506122-A EXTRACTING PURINE OR PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE FROM CULTURE OF BACILLUS STEAROTHERMOPHILUS AND USED FOR FORMING NUCLEOSIDES BY REACTING PURINE OR PYRIMIDINE BASE, AS SACCHARIDE RESIDUE AND PHOPHORIC ACID YAMASA SHOYU KABUSHIKI KAISHA (JP) 1996-04-09 US disclosed
US-5384251-A Culture of Bacillus to produce nucleoside phosphorylase YAMASA SHOYU KABUSHIKI KAISHA (JP) 1995-01-24 US disclosed
US-5258301-A Nucleoside phosphorylase from Bacillus YAMASA SHOYU KABUSHIKI KAISHA (JP) 1993-11-02 US disclosed
EP-0411158-A1 Process for producing nucleosides by using phosphorylases obtainable from Bacillus stearothermophilus Yamasa Shoyu Kabushiki Kaisha (Yamasa Corporation) (JP) 1991-02-06 EP disclosed
EP-0233493-A2 Process for producing ribonucleosides Yamasa Shoyu Kabushiki Kaisha (JP) 1987-08-26 EP disclosed
US-4269839-A MUSCLE RELAXANTS AND ANTISPASMODIC AGENTS; RESPIRATORY SYSTEM DISORDERS BRISTOL-MYERS COMPANY (US) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140977-A1 REVERSIBLE TERMINATORS RNGTT, TYMP, TYMS MPO 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.