SCHEMBL887191

SCHEMBL887191

CC(=O)OC[C@H](N)C(=O)S

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 5/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
TSHR P16473 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL683686 0.81 TDP1 (0.43) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL419528 0.81 TDP1 (0.43) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL27878979 0.80 TDP1 (0.39) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL770416 0.79 NOS3 (0.56) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL770417 0.79 NOS3 (0.56) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL598363 0.79 NOS3 (0.56) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL8363277 0.79 NOS3 (0.43) TDP1ALDH1A1LMNAHSD17B10NOS3
SCHEMBL9980878 0.79 NOS3 (0.56) TDP1ALDH1A1LMNAHSD17B10NOS3
Hydrochloric Acid SCHEMBL7592766 0.77 NOS1 (0.55) TDP1ALDH1A1LMNAHSD17B10NOS3
Hydrogen Sulfide SCHEMBL22463012 0.77 NOS3 (0.55) TDP1ALDH1A1LMNAHSD17B10NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2380988-A2 Transgenic plants with enhanced agronomic traits Mosanto Technology LLC (US) 2011-10-26 EP disclosed
US-8039947-B2 Integrated circuit package system with different mold locking features STATS CHIPPAC LTD. (SG) 2011-10-18 US disclosed
US-8039690-B2 Stress-regulated genes of plants, transgenic plants containing same, and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2011-10-18 US disclosed
US-20100287671-A1 Stress-regulated genes of plants, transgenic plants containing same, and methods of use HARPER JEFFREY F 2010-11-11 US disclosed
US-7692065-B2 Stress-regulated genes of plants, transgenic plants containing same, and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2010-04-06 US disclosed
US-20060183137-A1 Stress-regulated genes of plants, transgenic plants containing same, and methods of use THE SCRIPPS RESEARCH INSTITUTE 2006-08-17 US disclosed
EP-1402037-A1 PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS Syngenta Participations AG (CH) 2004-03-31 EP disclosed
US-6593114-B1 Fragment comprising contiguous nucleotides; given nucleotide sequence HUMAN GENOME SCIENCES, INC. 2003-07-15 US disclosed
EP-1313867-A2 STRESS-REGULATED GENES OF PLANTS, TRANSGENIC PLANTS CONTAINING SAME, AND METHODS OF USE The Scripps Research Institute (US) 2003-05-28 EP disclosed
WO-2002016655-A9 STRESS-REGULATED GENES OF PLANTS, TRANSGENIC PLANTS CONTAINING SAME, AND METHODS OF USE SCRIPPS RESEARCH INST (US) 2003-01-09 WO disclosed
WO-2003000898-A1 PLANT GENES INVOLVED IN DEFENSE AGAINST PATHOGENS SYNGENTA PARTICIPATIONS AG (CH) 2003-01-03 WO disclosed
WO-2002016655-A2 STRESS-REGULATED GENES OF PLANTS, TRANSGENIC PLANTS CONTAINING SAME, AND METHODS OF USE THE SCRIPPS RESEARCH INSTITUTE (US) 2002-02-28 WO disclosed