Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683686 | 1.00 | TDP1 (0.43) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL770417 | 0.83 | NOS3 (0.56) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL598363 | 0.83 | NOS3 (0.56) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL9980878 | 0.83 | NOS3 (0.56) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL770416 | 0.83 | NOS3 (0.56) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL8363277 | 0.83 | NOS3 (0.43) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| SCHEMBL12662808 | 0.81 | TSHR (0.39) | NOS3NOS1NOS2TSHR | |
| SCHEMBL887191 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| Hydrogen Sulfide SCHEMBL22463012 | 0.81 | NOS3 (0.55) | TDP1ALDH1A1LMNAHSD17B10NOS3 | |
| Hydrochloric Acid SCHEMBL7592766 | 0.81 | NOS1 (0.55) | TDP1ALDH1A1LMNAHSD17B10NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150126568-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERTENSION AND MANAGEMENT OF DIABETIC KIDNEY DISEASE | KANDULA MAHESH (IN) | 2015-05-07 | — | — | US | disclosed |
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126568-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HYPERTENSION AND MANAGEMENT OF DIABETIC KIDNEY DISEASE | REN, SLC5A1, SLC5A2 | TDP1 4378/4885ALDH1A1 1864/4885LMNA 1638/4885 |
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | TDP1 2649/4885ALDH1A1 1739/4885LMNA 1458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.