Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 15/20 | 0.47 |
| ▸ | HTR7 | P34969 | 15/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786866 | 0.86 | ACHE (0.50) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8788039 | 0.84 | SLC18A3 (0.48) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8787796 | 0.84 | ACHE (0.48) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8506902 | 0.84 | ACHE (0.50) | DRD2SLC6A4HTR2AKCNH2ACHE | |
| SCHEMBL8788032 | 0.83 | DRD2 (0.47) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8788836 | 0.83 | DRD2 (0.43) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8787553 | 0.83 | ACHE (0.47) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8789335 | 0.82 | ACHE (0.47) | DRD2SLC6A4HTR2AHTR7KCNH2 | |
| SCHEMBL8787897 | 0.82 | ACHE (0.48) | DRD2SLC6A4HTR2AKCNH2ACHE | |
| SCHEMBL8789187 | 0.81 | HTR2A (0.42) | DRD2SLC6A4HTR2AHTR7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591745-A | ANTIPSYCHOTICS AND ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1997-01-07 | — | — | US | disclosed |