Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16487838 | 0.77 | PTGS1 (0.51) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL938217 | 0.76 | RAB9A (0.40) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL2611106 | 0.76 | PKM (0.45) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL3279759 | 0.76 | KDM4E (0.42) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL365942 | 0.76 | RAB9A (0.40) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL365941 | 0.74 | KDM4E (0.44) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL16347374 | 0.74 | PTGS1 (0.39) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL1463361 | 0.74 | HDAC3 (0.41) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL946905 | 0.74 | KMT2A (0.45) | RAB9ANPC1HDAC3HDAC4HDAC1 | |
| SCHEMBL16705384 | 0.74 | RAB9A (0.42) | RAB9ANPC1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143026-B1 | COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS | NOVARTIS AG (CH) | 2024-07-10 | — | — | EP | disclosed |
| US-5698495-A | Herbicidal substituted pyrazole compounds | ZENECA LIMITED (GB) | 1997-12-16 | — | — | US | disclosed |