Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493311 | 0.83 | KMT2A (0.34) | KMT2AKDM4E | |
| SCHEMBL21653347 | 0.80 | GRN (0.50) | NPC1KDM4ELMNA | |
| SCHEMBL16487838 | 0.77 | PTGS1 (0.51) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL2611106 | 0.76 | PKM (0.45) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL938217 | 0.76 | RAB9A (0.40) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL365942 | 0.76 | RAB9A (0.40) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL3279759 | 0.76 | KDM4E (0.42) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL21720871 | 0.75 | PTGS2 (0.37) | KMT2APTGS2PTGS1KDM4ELMNA | |
| SCHEMBL757069 | 0.75 | RAB9A (0.47) | KMT2APTGS2PTGS1RAB9ANPC1 | |
| SCHEMBL1463361 | 0.74 | HDAC3 (0.41) | KMT2APTGS2PTGS1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103951663-B | Containing replacing the pyrazole amide of 1,3,4-thiadiazoles thioether and pyrazole imine analog derivative and preparation method and application | 贵州大学 | 2016-08-17 | — | — | CN | claimed |
| US-20180215713-A1 | AMINOBENZAMIDE DERIVATIVES AS USEFUL AGENTS FOR CONTROLLING ANIMAL PARASITES | VIRBAC (FR) | 2018-08-02 | — | — | US | disclosed |
| US-9944604-B2 | Aminobenzamide derivatives as useful agents for controlling animal parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-04-17 | — | — | US | disclosed |
| EP-3181558-A1 | SUBSTITUTED [1,2,4]TRIAZOLE COMPOUNDS AND THEIR USE AS FUNGICIDES | BASF SE (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-9670192-B2 | Substituted isoxazole derivatives | BASF SE (DE) | 2017-06-06 | — | — | US | disclosed |
| CN-103951663-B | Containing replacing the pyrazole amide of 1,3,4-thiadiazoles thioether and pyrazole imine analog derivative and preparation method and application | 贵州大学 | 2016-08-17 | — | — | CN | disclosed |
| US-20160096829-A1 | Substituted Isoxazole Derivatives | BASF SE (DE) | 2016-04-07 | — | — | US | disclosed |
| US-20150351401-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-20150351399-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| CN-103613583-B | 1,3-substituting group-4-substituted pyrazolecarboxylic acylhydrazone and its preparation method and application | GUIZHOU UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| CN-101273009-B | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG | 2012-09-05 | — | — | CN | disclosed |
| US-20120214851-A1 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasites | BAYER CROPSCIENCE AG (DE) | 2012-08-23 | — | — | US | disclosed |
| US-7964735-B2 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2011-06-21 | — | — | US | disclosed |
| US-20110009457-A1 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasistes | BAYER CROPSCIENCE AG (DE) | 2011-01-13 | — | — | US | disclosed |
| CN-101903350-A | Aminobenzamide derivatives as useful agents for controlling animal parasites | BAYER CROPSCIENCE AG | 2010-12-01 | — | — | CN | disclosed |
| EP-2225206-A2 | AMINOBENZAMIDE DERIVATIVES AS USEFUL AGENTS FOR CONTROLLING ANIMAL PARASITES | Bayer CropScience Aktiengesellschaft (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| WO-2009080203-A2 | AMINOBENZAMIDE DERIVATIVES AS USEFUL AGENTS FOR CONTROLLING ANIMAL PARASITES | BAYER CROPSCIENCE AG (DE) | 2009-07-02 | — | — | WO | disclosed |
| EP-2072501-A1 | Aminobenzamide derivatives as useful agents for controlling animal parasites | Bayer CropScience AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| CN-101273009-A | Insecticidal 3-acylaminobenzanilides | BAYER CROPSCIENCE AG (DE) | 2008-09-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150351401-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | CYP1B1, CYP4B1, COX4I1 | KMT2A 2322/4885PTGS2 1160/4885PTGS1 724/4885 |
| US-20180215713-A1 | AMINOBENZAMIDE DERIVATIVES AS USEFUL AGENTS FOR CONTROLLING ANIMAL PARASITES | AADAT, PIGS, SLC1A5 | KMT2A 166/4885PTGS2 519/4885PTGS1 747/4885 |
| US-20110009457-A1 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasistes | PIGS, AADAT, PIGT | KMT2A 252/4885PTGS2 1066/4885PTGS1 939/4885 |
| US-20120214851-A1 | Aminobenzamide Derivatives as Useful Agents for Controlling Animal Parasites | AADAT, PIGS, SLC1A5 | KMT2A 166/4885PTGS2 519/4885PTGS1 747/4885 |
| US-20160096829-A1 | Substituted Isoxazole Derivatives | COX4I1, CYP4X1, TBXA2R | KMT2A 2529/4885PTGS2 1071/4885PTGS1 1372/4885 |
| US-20150351399-A1 | SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS | CYP4B1, CYP1B1, CYP3A4 | KMT2A 2242/4885PTGS2 1125/4885PTGS1 703/4885 |
| US-20090215623-A1 | Insecticidal 3-acylaminobenzanilides | CBR3, AADAC, DDT | KMT2A 1245/4885PTGS2 3905/4885PTGS1 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.