Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31710835 | 0.90 | NFE2L2 (0.52) | NFE2L2L3MBTL1CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL62156 | 0.90 | NFE2L2 (0.52) | NFE2L2L3MBTL1CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL14562456 | 0.90 | NFE2L2 (0.52) | NFE2L2L3MBTL1CYP1A1CYP1A2CYP2D6 | |
| Glycine SCHEMBL4305397 | 0.84 | NFE2L2 (0.46) | NFE2L2L3MBTL1KMT2AMAOBMEN1 | |
| SCHEMBL28358728 | 0.84 | NFE2L2 (0.38) | NFE2L2L3MBTL1TRPM8KMT2AMEN1 | |
| SCHEMBL3008171 | 0.82 | NFE2L2 (0.44) | NFE2L2L3MBTL1CYP1A1CYP1A2CYP2D6 | |
| SCHEMBL14645363 | 0.82 | SMN1; SMN2 (0.48) | NFE2L2L3MBTL1CYP1A2KMT2APPARG | |
| SCHEMBL19137920 | 0.80 | NFKB1 (0.47) | NFE2L2ALOX5KMT2AMEN1MAPT | |
| SCHEMBL887236 | 0.80 | MAPT (0.54) | L3MBTL1CYP1A1CYP1A2CYP2D6KMT2A | |
| SCHEMBL2226672 | 0.79 | NFE2L2 (0.60) | NFE2L2L3MBTL1CYP1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405886-A1 | TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Isp Investments Inc. (US) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010105052-A1 | TOPICAL PERSONAL CARE AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS INC. (US) | 2010-09-16 | — | — | WO | disclosed |