SCHEMBL887320

SCHEMBL887320

Cc1ccc(S(=O)(=O)N(C(C)C(C)N)P(=O)(O)S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AGER Q15109 1/20 0.42
MMP2 P08253 3/20 0.39
CA12 O43570 3/20 0.39
CA9 Q16790 3/20 0.39
CA14 Q9ULX7 1/20 0.39
MMP9 P14780 2/20 0.37
MMP8 P22894 2/20 0.37
MMP13 P45452 2/20 0.37
MMP1 P03956 1/20 0.37
MMP3 P08254 1/20 0.37
MMP7 P09237 1/20 0.37
MMP14 P50281 1/20 0.37
MAPT P10636 2/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
GBA1 P04062 1/20 0.36
POLB P06746 1/20 0.36
C5AR1 P21730 1/20 0.36
PTPN1 P18031 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887371 0.85 AGER (0.41) AGERMMP2CA12CA9CA14
SCHEMBL887317 0.77 CA12 (0.39) AGERMMP2CA12CA9CA14
SCHEMBL887315 0.74 TSHR (0.38) AGERPOLBMEN1KMT2ACNR2
SCHEMBL887369 0.68 GAA (0.52) AGERMMP2CA12CA9CA14
SCHEMBL6092041 0.67 MAPT (0.47) AGERMMP2CA12CA9CA14
SCHEMBL12180441 0.66 AGER (0.71) AGERCA12CA9MAPTMCOLN3
SCHEMBL3278846 0.65 AGER (0.53) AGERMMP2CA12CA9MMP9
SCHEMBL15548655 0.64 CA12 (0.53) MMP2CA12CA9CA14MMP9
SCHEMBL1322704 0.63 AGER (0.52) AGERMMP2CA12CA9MMP9
SCHEMBL9187490 0.63 GLA (0.53) AGERCA12CA9MAPTMCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902207-B2 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed
US-20070142639-A1 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142639-A1 Process for production of amines SMS, CCNT1, PEAK1 AGER 1139/4885MMP2 3804/4885CA12 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.