Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487444 | 0.80 | AGER (0.52) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL14350865 | 0.79 | PKM (0.52) | GAAKEAP1NFE2L2CA1CA2 | |
| SCHEMBL3278846 | 0.78 | AGER (0.53) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL12180441 | 0.75 | AGER (0.71) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL1275171 | 0.74 | SNCA (0.47) | AGERMAPTGAACA12CA9 | |
| SCHEMBL28258824 | 0.74 | AGER (0.50) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL5909694 | 0.74 | AGER (0.46) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL9811625 | 0.74 | MAPT (0.57) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL30121315 | 0.74 | GAA (0.54) | AGERMAPTMCOLN3C5AR1GAA | |
| SCHEMBL25678915 | 0.73 | GAA (0.48) | AGERMAPTMCOLN3GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058329-B2 | as flameproofing agents for polymers such as polyesters, polyamides, polycarbonates, polystyrenes, polyethylene, polypropylene, phenolic and epoxy resins | Schill+Seilacher “Struktol” Aktiengesellschaft (DE) | 2011-11-15 | — | — | US | claimed |
| EP-1866320-B1 | NITROGEN-CONTAINING BRIDGED DERIVATIVES OF 6H-DIBENZ(E,E)(1,2)-OXAPHOSPHORINE-6-OXIDES METHOD FOR PRODUCTION AND USE THEREOF AS FLAME-RETARDANT AGENTS | SCHILL & SEILACHER STRUKTOL AG (DE) | 2009-02-18 | — | — | EP | claimed |
| US-20080167405-A1 | Nitrous Bridged Derivatives of 6H-Dibenz[C,E][1,2]-Oxaphosphorine-6-Oxides, Process For the Preparation and Use Thereof | SCHILL+SEILACHER "STRUKTOL" AKTIENGESELLSCHAFT (DE) | 2008-07-10 | — | — | US | claimed |
| EP-0325762-B1 | Macrocyclic chelating agents and chelates thereof | BRACCO SPA (IT) | 1995-03-22 | — | — | EP | claimed |
| EP-0325762-B1 | Macrocyclic chelating agents and chelates thereof | BRACCO SPA (IT) | 1995-03-22 | — | — | EP | disclosed |
| US-5132409-A | Derivatives of 1,4,7,10-Tetraazacyclododecane | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1992-07-21 | — | — | US | disclosed |
| EP-0325762-A1 | Macrocyclic chelating agents and chelates thereof | BRACCO S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167405-A1 | Nitrous Bridged Derivatives of 6H-Dibenz[C,E][1,2]-Oxaphosphorine-6-Oxides, Process For the Preparation and Use Thereof | PFAS, PCBP1, DNPH1 | AGER 4109/4885MAPT 3116/4885MCOLN3 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.