Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29989592 | 0.87 | RAB9A (0.77) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL527994 | 0.87 | RAB9A (0.77) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL3225418 | 0.83 | BRD4 (0.55) | NAMPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11309226 | 0.83 | HDAC1 (0.66) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL31711699 | 0.83 | HDAC1 (0.66) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL11316188 | 0.83 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL8493065 | 0.82 | ALDH1A1 (0.59) | NAMPTKMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6774791 | 0.80 | BRD4 (0.55) | NAMPTMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL28185207 | 0.80 | NPC1 (0.67) | MEN1KMT2ANPC1RAB9APABPC1 | |
| SCHEMBL8522485 | 0.80 | TSHR (0.56) | MEN1KMT2ANPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593994-A | ANTIINFLAMMATORY AGENTS | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996010012-A1 | NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-04-04 | — | — | WO | disclosed |