SCHEMBL8874228

SCHEMBL8874228

Cc1nc(C)c2c(c1C)C(=O)OC2=O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31634625 0.73 TSHR (0.43) TSHRALDH1A1
SCHEMBL411125 0.73 TSHR (0.43) TSHRALDH1A1
SCHEMBL24316717 0.67 TDP2 (0.38) TSHRALDH1A1
SCHEMBL12869481 0.66 TSHR (0.41) TSHRALDH1A1
SCHEMBL31633611 0.66 ALOX15 (0.34) ALDH1A1
SCHEMBL31633616 0.64 TSHR (0.31) TSHRALDH1A1
SCHEMBL9750690 0.64 MAPT (0.31)
SCHEMBL13415489 0.63 ALOX15 (0.42) TSHRALDH1A1
SCHEMBL30971006 0.63 TSHR (0.35) TSHRALDH1A1
SCHEMBL15801317 0.63 TSHR (0.35) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192327-A Preparation method of pyridine dicarboxylic anhydride solution 张家港市国泰华荣化工新材料有限公司 2025-06-24 CN disclosed
US-5621027-A Dyestuffs for bulk dyeing plastics BAYER AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed