SCHEMBL9750690

SCHEMBL9750690

Cc1nc2c(nc1C)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752531 0.71 EGFR (0.31)
SCHEMBL4068697 0.71 JAK3 (0.33)
SCHEMBL8661034 0.70 TYMS (0.33)
SCHEMBL9357079 0.67 MAPT (0.52) MAPT
SCHEMBL3927195 0.65 ALDH1A1 (0.44) MAPT
SCHEMBL8371624 0.65 S100A4 (0.48)
SCHEMBL261649 0.64 S100A4 (0.52)
SCHEMBL10373895 0.64 MEN1 (0.50) MAPT
SCHEMBL8874228 0.64 TSHR (0.33)
SCHEMBL22654547 0.63 ALOX15 (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226065-A1 ANTI-INFLAMMATORY COMPOSITIONS, METHODS AND USES THEREOF COMVITA LIMITED (NZ) 2023-07-20 US disclosed
US-20230226065-A1 ANTI-INFLAMMATORY COMPOSITIONS, METHODS AND USES THEREOF COMVITA LIMITED (NZ) 2023-07-20 US disclosed
WO-2022005308-A1 ANTI-INFLAMMATORY COMPOSITIONS, METHODS AND USES THEREOF COMVITA LIMITED (NZ) 2022-01-06 WO disclosed
WO-2021002763-A1 USE OF A COMPOSITION COMPRISING 3,6,7-TRIMETHYLLUMAZINE FOR PREVENTING, AMELIORATING OR TREATING MMP-9 ASSOCIATED CONDITIONS AND INFLAMMATION COMVITA LIMITED (NZ) 2021-01-07 WO disclosed
WO-2017099612-A1 MARKER COMPOUNDS OF LEPTOSPERMUM HONEYS AND METHODS OF ISOLATION AND ASSAYING THEREOF COMVITA LIMITED (NZ) 2017-06-15 WO disclosed
US-5041547-A Color formers in pressure or heat sensitive recording materials; discoloration inhibition; color fastness APPLETON PAPERS INC. (US) 1991-08-20 US disclosed
EP-0192328-B1 CHROMOGENIC COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-09 EP disclosed
EP-0192328-A1 Chromogenic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226065-A1 ANTI-INFLAMMATORY COMPOSITIONS, METHODS AND USES THEREOF PTGES2, TPMT, PARK7 MAPT 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.