Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862969 | 0.99 | ICMT (0.44) | ICMTARMRGPRX4MEN1KMT2A | |
| SCHEMBL9211432 | 0.85 | NR1I2 (0.41) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11035928 | 0.84 | L3MBTL1 (0.48) | MEN1KMT2ATDP1NPC1RAB9A | |
| SCHEMBL9863089 | 0.84 | MRGPRX4 (0.42) | MRGPRX4MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8874236 | 0.83 | MEN1 (0.42) | ICMTMRGPRX4MEN1KMT2ACYP11B1 | |
| SCHEMBL11034112 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9666814 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9436179 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL11031011 | 0.83 | CYP1A2 (0.46) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL9862918 | 0.82 | CYP1A2 (0.47) | MEN1KMT2ACYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |