Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | FOS | P01100 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874572 | 1.00 | MEN1 (0.52) | MEN1KMT2AALDH1A1FOSJUN | |
| SCHEMBL20212425 | 0.84 | NFKB1 (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8953422 | 0.84 | NFKB1 (0.45) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4886670 | 0.84 | AKR1C3 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4886664 | 0.84 | AKR1C3 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4886669 | 0.84 | AKR1C3 (0.43) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL8653627 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1FOSJUN | |
| SCHEMBL8653628 | 0.83 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1FOSJUN | |
| SCHEMBL20397706 | 0.79 | KDM4E (0.39) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL18833343 | 0.78 | KDM4E (0.36) | ALDH1A1JUNMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |