Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886669 | 1.00 | AKR1C3 (0.43) | AKR1C3AKR1C2RECQLNPC1RAB9A | |
| SCHEMBL4886670 | 1.00 | AKR1C3 (0.43) | AKR1C3AKR1C2RECQLNPC1RAB9A | |
| SCHEMBL4883097 | 0.89 | SMN1; SMN2 (0.40) | AKR1C3AKR1C2RECQLNPC1RAB9A | |
| SCHEMBL8364996 | 0.89 | SMN1; SMN2 (0.40) | AKR1C3AKR1C2RECQLNPC1RAB9A | |
| SCHEMBL20212425 | 0.85 | NFKB1 (0.45) | AKR1C3NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8953422 | 0.85 | NFKB1 (0.45) | AKR1C3NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL8874572 | 0.84 | MEN1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL8874576 | 0.84 | MEN1 (0.52) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL18063268 | 0.82 | NPC1 (0.40) | RECQLNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18063266 | 0.82 | NPC1 (0.40) | RECQLNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | AICURIS GMBH & CO. KG (DE) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275018-A1 | ANTIBACTERIAL AMIDE-MACROCYCLES V | ARG1, HRH3, H1-0 | AKR1C3 603/4885AKR1C2 1392/4885RECQL 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.