Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874795 | 1.00 | MAPK9 (0.54) | MAPK9TAS1R3TAS1R1NPC1PKM | |
| SCHEMBL5407656 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1NPC1PKMRAB9A | |
| SCHEMBL17822666 | 0.84 | TAS1R3 (0.62) | TAS1R3TAS1R1NPC1PKMRAB9A | |
| SCHEMBL4880917 | 0.82 | TAS1R3 (0.60) | TAS1R3TAS1R1NPC1PKMRAB9A | |
| SCHEMBL31611734 | 0.80 | TAS1R3 (0.78) | TAS1R3TAS1R1PKMSMN1; SMN2MEN1 | |
| SCHEMBL8873750 | 0.80 | ALDH1A1 (0.47) | MAPK9RAB9AALDH1A1MAPK1MEN1 | |
| SCHEMBL10346803 | 0.80 | NPC1 (0.53) | MAPK9TAS1R3TAS1R1NPC1PKM | |
| SCHEMBL11142926 | 0.76 | TAS1R3 (0.67) | TAS1R3TAS1R1NPC1PKMRAB9A | |
| SCHEMBL14262002 | 0.75 | GAA (0.67) | MAPK9TAS1R3TAS1R1SMN1; SMN2ALDH1A1 | |
| SCHEMBL25496973 | 0.74 | TAS1R3 (0.78) | TAS1R3TAS1R1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |