Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738260 | 0.79 | THRB (0.47) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL5823373 | 0.79 | MEN1 (0.45) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL1090847 | 0.79 | THRB (0.59) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL25246107 | 0.77 | THRB (0.48) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL346323 | 0.77 | THRB (0.48) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL8874054 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNATSHR | |
| SCHEMBL9259866 | 0.76 | THRB (0.47) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL21523649 | 0.76 | MEN1 (0.45) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL12775995 | 0.76 | THRB (0.47) | ALDH1A1TP53HPGDMEN1KMT2A | |
| SCHEMBL13962011 | 0.76 | THRB (0.47) | ALDH1A1TP53HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643929-A | TREATMENT OF PICORNAVIRAL OR RHINOVIRUS AND CHEMICAL INTERMEDIATES | SANOFI WINTHROP, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5464848-A | 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1995-11-07 | — | — | US | disclosed |