Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873365 | 0.80 | TACR1 (0.46) | CHRM4TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL8873598 | 0.79 | MEN1 (0.46) | CHRM4TACR1MEN1KMT2ACHRM2 | |
| SCHEMBL8875023 | 0.78 | TACR1 (0.45) | CHRM4TACR1MEN1KMT2AMAPT | |
| SCHEMBL8874334 | 0.78 | TACR1 (0.40) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8874475 | 0.77 | TACR1 (0.57) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8875025 | 0.76 | GAA (0.46) | TACR1 | |
| SCHEMBL8874365 | 0.75 | GAA (0.44) | TACR1MEN1KMT2ACYP3A4MAPT | |
| SCHEMBL8875138 | 0.74 | SIGMAR1 (0.46) | CHRM4TACR1MEN1KMT2ACYP3A4 | |
| SCHEMBL8875275 | 0.74 | CHRM4 (0.40) | CHRM4TACR1MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8874853 | 0.73 | SIGMAR1 (0.45) | CHRM4TACR1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |