Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875025 | 0.83 | GAA (0.46) | TACR1GAADRD2DRD3FUCA1 | |
| SCHEMBL8874365 | 0.82 | GAA (0.44) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9003052 | 0.80 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9003055 | 0.80 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9268452 | 0.80 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL8875253 | 0.78 | CHRM4 (0.44) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729134 | 0.75 | TACR1 (0.39) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729281 | 0.75 | MEN1 (0.43) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729382 | 0.73 | DPP4 (0.46) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL8873797 | 0.73 | FAAH (0.35) | MEN1CYP3A4MAPTTSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |