Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875566 | 0.92 | CDK1 (0.41) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL8875166 | 0.84 | KDM4E (0.32) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8883710 | 0.70 | CDK1 (0.40) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL613041 | 0.68 | CDK1 (0.41) | CDK1CCNB1CCNE1CDK2KDM4E | |
| SCHEMBL31470158 | 0.68 | CDK1 (0.41) | CDK1CCNB1CCNE1CDK2KDM4E | |
| SCHEMBL11812075 | 0.68 | CDK1 (0.46) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL7904142 | 0.67 | CDK1 (0.34) | CDK1CCNB1CCNE1CDK2KDM4E | |
| SCHEMBL612105 | 0.67 | ALDH1A1 (0.34) | KDM4EKMT2AALDH1A1GLA | |
| SCHEMBL8874891 | 0.67 | CDK1 (0.38) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL4061806 | 0.67 | ADORA2B (0.34) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639881-A | ANTITUMOR AGENTS, TREATMENT OF BREAST CANCER | ARIZONA BOARD OF REGENTS ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1997-06-17 | — | — | US | disclosed |