Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267634 | 1.00 | HSD17B10 (0.51) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL19122600 | 0.98 | HSD17B10 (0.49) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL8875728 | 0.93 | TRPV4 (0.46) | HSD17B10TSHRTRPV4ALDH1A1SIGMAR1 | |
| SCHEMBL18923563 | 0.89 | HSD17B10 (0.53) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL24776881 | 0.86 | TRPV4 (0.48) | TRPV4SIGMAR1KCNH2NOS3NOS1 | |
| SCHEMBL6513061 | 0.85 | HSD17B10 (0.56) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL25698390 | 0.85 | HSD17B10 (0.56) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL17818519 | 0.85 | HSD17B10 (0.56) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL28826019 | 0.83 | HSD17B10 (0.53) | HSD17B10TSHRESR1ADRA2AADORA3 | |
| SCHEMBL6231115 | 0.81 | TSHR (0.44) | HSD17B10TSHRALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |