Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122600 | 0.95 | HSD17B10 (0.49) | TRPV4NOS3NOS1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24267634 | 0.93 | HSD17B10 (0.51) | TRPV4NOS3NOS1ALDH1A1TSHR | |
| SCHEMBL8875503 | 0.93 | HSD17B10 (0.51) | TRPV4NOS3NOS1ALDH1A1TSHR | |
| SCHEMBL24776881 | 0.89 | TRPV4 (0.48) | TRPV4NOS3NOS1SIGMAR1KCNJ1 | |
| SCHEMBL6231115 | 0.88 | TSHR (0.44) | SMN1; SMN2NPC1HPGDRAB9ANPSR1 | |
| SCHEMBL10334702 | 0.84 | HSD17B10 (0.46) | SMN1; SMN2NPC1HPGDRAB9ANPSR1 | |
| SCHEMBL12189123 | 0.82 | TRPV4 (0.52) | TRPV4NOS3NOS1KCNJ1KCNH2 | |
| SCHEMBL18923563 | 0.81 | HSD17B10 (0.53) | ALDH1A1TSHRHSD17B10SIGMAR1KCNH2 | |
| SCHEMBL13953242 | 0.81 | TRPV4 (0.41) | TRPV4NOS3NOS1SIGMAR1KCNJ1 | |
| SCHEMBL3914612 | 0.81 | SKP2 (0.56) | NOS3NOS1SMN1; SMN2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |