Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875770 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PTPRACYP2C19SLC1A5LMNA | |
| SCHEMBL8875762 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PTPRACYP2C19SLC1A5LMNA | |
| SCHEMBL9270543 | 0.83 | L3MBTL1 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9270545 | 0.83 | L3MBTL1 (0.50) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8964199 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP2C19LMNAMAPTMEN1 | |
| SCHEMBL7375715 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL30013379 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL29785614 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL7885274 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL8874631 | 0.80 | AGTR2 (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658943-A | VASODILATOR FOR CARDIOVASCULAR DISORDER, HYPOTENSIVE AGENT | WARNER-LAMBERT COMPANY (US) | 1997-08-19 | — | — | US | disclosed |