Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876139 | 0.90 | VHL (0.42) | POLBKMT2AALDH1A1LMNACACNA1A | |
| SCHEMBL8877540 | 0.89 | POLB (0.38) | POLBKMT2AALDH1A1LMNACACNA1A | |
| SCHEMBL8876637 | 0.88 | POLB (0.40) | POLBKMT2AALDH1A1CACNA1ACACNA2D1 | |
| SCHEMBL8876386 | 0.88 | CTSS (0.40) | CTSSCTSKKMT2AALDH1A1LMNA | |
| SCHEMBL8878158 | 0.87 | POLB (0.36) | POLBKMT2AALDH1A1LMNACACNA1A | |
| SCHEMBL8875741 | 0.85 | ALDH1A1 (0.38) | POLBCTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL8876253 | 0.83 | KMT2A (0.38) | POLBCTSSCTSKKMT2AALDH1A1 | |
| SCHEMBL8877372 | 0.82 | KMT2A (0.34) | POLBKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL8313957 | 0.81 | ALDH1A1 (0.33) | POLBKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL8877494 | 0.81 | KMT2A (0.50) | POLBCTSSCTSKKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |